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Structural Aspects of Transmembrane Domain Interactions of Receptor Tyrosine Kinases

โœ Scribed by Bocharov, Eduard; Mineev, Konstantin; Lesovoy, Dmitry; Goncharuk, Marina; Goncharuk, Sergey; Bocharova, Olga; Volynsky, Pavel; Efremov, Roman; Arseniev, Alexander


Book ID
122233927
Publisher
Biophysical Society
Year
2011
Tongue
English
Weight
62 KB
Volume
100
Category
Article
ISSN
0006-3495

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Structural analysis of receptor tyrosine
โœ Stevan R Hubbard ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 948 KB

Receptor tyrosine kinases (RTKs) are single-pass transmembrane receptors that possess intrinsic cytoplasmic enzymatic activity, catalyzing the transfer of the g-phosphate of ATP to tyrosine residues in protein substrates. RTKs are essential components of signal transduction pathways that aect cell p