Structural anomalies of the X chromosome and inactivation center
β Scribed by M. G. Mattei; J. F. Mattei; I. Vidal; F. Giraud
- Book ID
- 104697876
- Publisher
- Springer
- Year
- 1981
- Tongue
- English
- Weight
- 638 KB
- Volume
- 56
- Category
- Article
- ISSN
- 0340-6717
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π SIMILAR VOLUMES
Cytogenetic analyses have previously shown that the region Xq11.2-q21 is retained in all structurally abnormal X chromosomes. From these observations the conclusion has been drawn that this "critical region" on the proximal long arm of the X chromosome contains the locus controlling X-inactivation.
## Location of an X-inactivation Centre in Mouse and Human Experiments utilising X-autosome translocations in or autosomal insertions into X chromosome material(") indicated that autosomal coat colour genes placed adjacent to X chromosome material could be inactivated resulting in coat colour vari