A phylogenetic approach to assessing the
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M.F. Santibáñez Koref; R. Gangeswaran; I.P. Santibáñez Koref; N. Shanahan; J.M.
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Article
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2003
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John Wiley and Sons
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English
⚖ 246 KB
The identification of deleterious mutations within candidate genes is a crucial step in the elucidation of the genetic bases of human disease. However, the significance of any base or amino acid change within a gene is unknown until detailed structural and functional analysis has been carried out. A