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Structural and mechanistic insights into the interaction between Rho and mammalian Dia

✍ Scribed by Rose, R.; Weyand, M.; Lammers, M.; Ishizaki, T.; Ahmadian, M. R.; Wittinghofer, A.


Book ID
109894287
Publisher
Nature Publishing Group
Year
2005
Tongue
English
Weight
459 KB
Volume
435
Category
Article
ISSN
0028-0836

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Structural insights into the interaction
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## Abstract The protein Cripto is the founding member of the extra‐cellular EGF–CFC growth factors, which are composed of two adjacent cysteine‐rich domains: the EGF‐like and the CFC. Members of the EGF–CFC family play key roles in embryonic development and are also implicated in tumourigenesis. Cr