Structural and immunological similarities between HLA antigens from three loci

Alteration of antigen-independent immuno

Alteration of antigen-independent immunologic synapse formation between dendritic cells from HLA–B27–transgenic rats and CD4+ T cells: Selective impairment of costimulatory molecule engagement by mature HLA–B27

✍ Cécile Hacquard-Bouder; Maria-Sole Chimenti; Benoît Giquel; Emmanuel Donnadieu; 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 417 KB 👁 1 views

## Abstract ## Objective To investigate the molecular mechanism responsible for the reduced capacity of dendritic cells (DCs) from HLA–B27–transgenic rats to form conjugates with naive T cells. ## Methods We monitored interactions between DCs derived from HLA–B27–transgenic, HLA–B7–transgenic co