Structural and functional importance of theβ-turn in proteins. Studies on proline-containing peptides
✍ Scribed by V. S. Ananthanarayanan; S. K. Attah-poku; P. L. Mukkamala; P. H. Rehse
- Book ID
- 112829240
- Publisher
- Indian Academy of Sciences
- Year
- 1985
- Tongue
- English
- Weight
- 620 KB
- Volume
- 8
- Category
- Article
- ISSN
- 0250-5991
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## Abstract Amino acids are known to differ in their individual preferences for each of the four positions of the β‐turn conformation formed by tetrapeptide segments. Proline and glycine show relatively high preferences for positions 2 and 3, respectively, of the β‐turn. Using tripeptides of the ty
## Abstract Peptide β‐hairpin formation is facilitated by centrally positioned D‐Pro‐Xxx segments. The synthetic peptides Boc‐Leu‐Phe‐Val‐D‐Pro‐Ac~6~c‐Leu‐Phe‐Val‐OMe (**1**) and Boc‐Leu‐Phe‐Val‐D‐Pro‐Ac~8~c‐Leu‐Phe‐Val‐OMe (**2**) were synthesized in order to explore the role of bulky 1‐aminocyclo