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Structural and functional diversity of lysyl oxidase and the LOX-like proteins

✍ Scribed by J. Molnar; K.S.K. Fong; Q.P. He; K. Hayashi; Y. Kim; S.F.T. Fong; B. Fogelgren; K. Molnarne Szauter; M. Mink; K. Csiszar


Book ID
108497844
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
366 KB
Volume
1647
Category
Article
ISSN
1570-9639

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Lysyl oxidase (LO), an extracellular enzyme catalysing the first step of collagen and elastin cross-linking, is transiently expressed by myofibroblasts during fibrosis. A cell model with features of myofibroblast was thus established for studying the regulation of LO. Two clones of the 3T6 fibroblas