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Structural and functional characterization of MERS coronavirus papain-like protease

✍ Scribed by Lin, Min-Han; Chuang, Shang-Ju; Chen, Chiao-Che; Cheng, Shu-Chun; Cheng, Kai-Wen; Lin, Chao-Hsiung; Sun, Chiao-Yin; Chou, Chi-Yuan

Book ID
125396999
Publisher
BioMed Central
Year
2014
Tongue
English
Weight
792 KB
Volume
21
Category
Article
ISSN
1021-7770

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✍ Matthew R. Groves; RenΓ© Coulombe; John Jenkins; Miroslaw Cygler πŸ“‚ Article πŸ“… 1998 πŸ› John Wiley and Sons 🌐 English βš– 468 KB

Synthetic peptides corresponding to the proregions of papain-like cysteine proteases have been shown to be good and selective inhibitors of their parental enzymes. The molecular basis for their selectivity, quite remarkable in some cases, is not fully understood. The recent determination of the crys