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Structural and Functional Characterization of Low-molecular-weight Heparins: Impact on the Development of Guidelines for Generic Products

✍ Scribed by Adiguzel, C.; Jeske, W. P.; Hoppensteadt, D.; Walenga, J. M.; Bansal, V.; Fareed, J.


Book ID
126201201
Publisher
SAGE Publications
Year
2009
Tongue
English
Weight
141 KB
Volume
15
Category
Article
ISSN
1076-0296

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## Abstract The matrix‐degrading enzyme aggrecanase has been identified in cartilage and is largely responsible for cartilage breakdown. The present study determined the efficacy of different heparin molecular weight fractions (HMWFs) and low molecular weight heparins (LMWHs) on aggrecanase activit