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Structural and Functional Analysis of Phosphothreonine-Dependent FHA Domain Interactions

✍ Scribed by Simon Pennell; Sarah Westcott; Miguel Ortiz-Lombardía; Dony Patel; Jiejin Li; Timothy J. Nott; Duaa Mohammed; Roger S. Buxton; Michael B. Yaffe; Chandra Verma; Stephen J. Smerdon


Book ID
113919048
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
822 KB
Volume
18
Category
Article
ISSN
0969-2126

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## Abstract __NKX‐3.1__ is a suspected prostate tumor suppressor gene that encodes a homeodomain transcripti on factor. NKX‐3.1 has been demonstrated to interact with prostate derived Ets factor (PDEF) and to suppress the ability of PDEF to transactivate the prostate specific antigen promoter. To d