The first synthesis of neu5Acα2-3Galβ1-4
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Ichiro Matsuo; Megumi Isomura; Katsumi Ajisaka
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Article
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1999
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Elsevier Science
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French
⚖ 212 KB
Glycopepfide (I), Neu5A~2-3Gall~l-4GlcNA~l-2Maactl-Ser, was synthesized using a chemoenzymatic strategy. Gal~l-4GlcNAcl~l\*2Man Ifisacd~ide was ~ using glycosidase assisted oligom:x:lutride synthesis. After coupling of this trisacchaxide with a sefine defivstive by chemical glycosylstion, sialic add