Strontium ranelate: a novel mode of action optimizing bone formation and resorption

Strontium ranelate: A novel mode of acti

Strontium ranelate: A novel mode of action leading to renewed bone quality

✍ Patrick Ammann 📂 Article 📅 2004 🏛 Springer-Verlag 🌐 English ⚖ 136 KB

Isolation and characterization of a cDNA

Isolation and characterization of a cDNA clone encoding a novel peptide (OSF) that enhances osteoclast formation and bone resorption

✍ Sakamuri Reddy; Rowena Devlin; Cheikh Menaa; Riko Nishimura; Sun Jin Choi; Mark 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 359 KB 👁 1 views

Using an expression cloning approach, we identified and cloned a novel intracellular protein produced by osteoclasts that indirectly induces osteoclast formation and bone resorption, termed OSF. Conditioned media from 293 cells transiently transfected with the 0.9 kb OSF cDNA clone stimulated osteoc