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Strongly basic macrocyclic triamines, 1,5,9-triazacyclododecanes for solvent extraction of gold(I) cyanide

✍ Scribed by Heung-Jin Choi; Yoon-Kyung Bae; Seok-Chan Kang; Yeon Sil Park; Joon Won Park; Woong-Il Kim; Thomas W Bell


Publisher
Elsevier Science
Year
2002
Tongue
French
Weight
139 KB
Volume
43
Category
Article
ISSN
0040-4039

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✦ Synopsis


Solvent extraction of gold(I) dicyanide anion from alkaline gold(I) cyanide solution using unusually basic amine extractants was conducted. 1,5,9-Triazacyclododecane (4) is known as an unusually basic macrocyclic amine having pK a =12.3-12.7, and is thus a good candidate as a basic amine extractant. Three lipophilic derivatives of 4 expected to stay in the organic phase during gold solvent extraction were synthesized. N-Dodecyl-1,5,9-triazacyclododecane (3) was prepared from 1,5,9-triazacyclododecane-2,4-dione (1) by N-alkylation with n-dodecyl iodide and then reduction with BH 3 -THF. N,N%-Didodecyl-1,5,9-triazacyclododecane (5) and N,N%,N%%-tridodecyl-1,5,9-triazacyclododecane (6) were efficiently synthesized by selective di-alkylation of 4 with n-dodecyl iodide, and by reductive alkylation of 4 with n-dodecanal, respectively. The extractants 3 and 6 showed pH 50 =10.5, which is the minimum value required for practical application.