## Abstract Natural killer (NK) cells are cytotoxic lymphocytes able to kill tumor cells and virusโinfected cells. Humanโresting NK cells can be activated by coโculture with NKโresistant CTVโ1a cells. These tumorโactivated cells (TaNKs) are cytotoxic to a range of NKโresistant tumor cells in vitro.
Strong natural killer (NK) cell activity in bone marrow of myeloma patients: Accelerated maturation of bone marrow NK cells and their interaction with other bone marrow cells
โ Scribed by Atsushi Uchida; Masato Yagita; Hiroyuki Sugiyama; Takashi Hoshino; Michael Moore
- Publisher
- John Wiley and Sons
- Year
- 1984
- Tongue
- French
- Weight
- 760 KB
- Volume
- 34
- Category
- Article
- ISSN
- 0020-7136
No coin nor oath required. For personal study only.
โฆ Synopsis
Bone marrow natural killer (NK) cell activity was lopoiesis and possibly in vivo hematopoiesis (Hansson studied in patients with multiple myeloma. Bone marrow et a[., 1982; Lotzo\ra et al,, 1979). mononuclear cells from myeloma patients expressed consjde.b levels of cytotoxicity K562 i n a , , s~=, .
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A study of 32 patients receiving cyclophosphamide (CY) and verapamil (VER) in addition to the drug combination vincristine, adriamycin and methyl prednisolone (VAMP) was made in which the clinical response and growth of clonogenic myeloma cells (MY-CFUJ from bone marrow aspirates were compared. At p