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Strong interaction between the effects of alcohol consumption and smoking on oesophageal squamous cell carcinoma among individuals with ADH1B and/or ALDH2 risk alleles

✍ Scribed by Yamamoto, K.; Suzuki, S.; Inoue, H.; Tsurumaru, M.; Kajiyama, Y.; Kato, H.; Igaki, H.; Furuta, K.; Fujita, H.; Tanaka, F.


Book ID
115549042
Publisher
BMJ Publishing Group
Year
2010
Tongue
English
Weight
456 KB
Volume
59
Category
Article
ISSN
0017-5749

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Carcinogenetic impact of ADH1B and ALDH2
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## Abstract The consumption of alcohol, tobacco and betel quid has been found to be an important contributor to esophageal squamous cell carcinoma (ESCC) in Taiwan. The genotoxic effect of the __ADH1B__ and __ALDH2__ genes modulating an individual's alcohol‐metabolizing capacity on ESCC may be link