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Strong indication for a breast cancer susceptibility gene on chromosome 8p12-p22: linkage analysis in German breast cancer families

✍ Scribed by Seitz, Susanne; Rohde, Klaus; Bender, Erhard; Nothnagel, Anita; Kölble, Konrad; Schlag, Peter M; Scherneck, Siegfried

Book ID: 110060530
Publisher: Nature Publishing Group
Year: 1997
Tongue: English
Weight: 402 KB
Volume: 14
Category: Article
ISSN: 0950-9232
DOI: 10.1038/sj.onc.1200881

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To date, 2 major breast cancer and/or ovarian cancer predisposition genes have been identified. However, a significant proportion of families with multiple cases of breast cancer cannot be explained by mutations in the BRCA1 and BRCA2 genes, 1 especially in the Nordic populations. [2][3][4] In addit