Stromal remodeling and SPARC (secreted protein acid rich in cysteine) expression in invasive ductal carcinomas of the breast
β Scribed by Peter J. Barth; Roland Moll; Annette Ramaswamy
- Publisher
- Springer
- Year
- 2005
- Tongue
- English
- Weight
- 246 KB
- Volume
- 446
- Category
- Article
- ISSN
- 1432-2307
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## Abstract ## BACKGROUND Secreted protein acidic and rich in cystein (SPARC) is a small extramatrixβassociated protein. Its production increases during angiogenesis and enhances matrix metalloproteinaseβ2 (MMPβ2) expression. The goal of this study was to show the clinical relevance of SPARC and i
## Abstract Periostin, a matricellular protein, is overexpressed in the stroma of several cancers. The aim of our study was to investigate more specifically whether periostin expression is associated with bone metastases from breast cancer and to determine its source in the affected bone. Nude mice