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Stromal-epithelial interactions prostate cancer cell invasion by altering the balance of metallopeptidase expression

✍ Scribed by Louise A Dawson; Norman J Maitland; Anthony J Turner; Badar A Usmani

Book ID: 118645143
Publisher: Elsevier Science
Year: 2003
Tongue: English
Weight: 92 KB
Volume: 2
Category: Article
ISSN: 1569-9056
DOI: 10.1016/s1569-9056(03)90510-0

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## Abstract We have previously demonstrated that Protein Kinase D1 (PKD1) interacts with E‐cadherin and is associated with altered cell aggregation and motility in prostate cancer (PC). Because both PKD1 and E‐cadherin are known to be dysregulated in PC, in this study we investigated the functional