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Striatal Plasticity and Basal Ganglia Circuit Function

✍ Scribed by Anatol C. Kreitzer; Robert C. Malenka


Book ID
116783272
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
537 KB
Volume
60
Category
Article
ISSN
0896-6273

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It has always been something of a mystery as to why different diseases of the basal ganglia may produce completely opposite effects on movement. Thus, defective dopaminergic inhibitory input into the striatum in Parkinson's disease causes an akinetic-rigid syndrome, while destruction of the striatum