Striatal glucose consumption in chorea-free subjects at risk of Huntington's disease
β Scribed by T. Kuwert; H. Boecker; H. Titz; H. Herzog; B. -C. Wang; U. Nayak; L. E. Feinendegen; H. W. Lange; A. Aulich
- Publisher
- Springer
- Year
- 1993
- Tongue
- English
- Weight
- 553 KB
- Volume
- 241
- Category
- Article
- ISSN
- 0340-5354
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## Abstract Both somatosensory evoked potentials (SEP) and striatal glucose consumption (rCMRGlc) measured by positron emission tomography (PET) have been reported to be abnormal early in the course of Huntington's disease (HD). To compare their diagnostic value, SEP and rCMRGlc were measured in a
A total of 27 different amino acids were determined in the fasting, morning lumbar CSF of 12 patients with Huntington's Disease (HD), 8 at-risk offspring and 16 non-choreic control patients. A significant (P less than 0.001) decrease was observed for asparagine, isoleucine, leucine, phenylalanine, h
originating from the peripheral rather than central retina. Correspondingly, VEP was also reported to be normal in MSA patients as it measures activity mainly originating from the central visual field. 7 Future studies will have to determine whether MSA patients show predominantly peripheral visual