Striatal dopamine transporter binding in patients with Parkinson's disease and severe occupational hydrocarbon exposure
β Scribed by M. Canesi; R. Benti; G. Marotta; R. Cilia; I. U. Isaias; P. Gerundini; G. Pezzoli; A. Antonini
- Book ID
- 111064955
- Publisher
- John Wiley and Sons
- Year
- 2007
- Tongue
- English
- Weight
- 475 KB
- Volume
- 0
- Category
- Article
- ISSN
- 1351-5101
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We measured striatal dopamine transporter binding using [(123)I]ioflupane and SPECT in patients with Parkinson's disease associated with the LRRK2 (PARK8) Gly2019Ser gene mutation (LRRK2-PD) and in gene-negative patients with idiopathic Parkinson's disease (IPD) of comparable disease duration and se
## Abstract We studied whether the ^123^IβFPβCIT uptake in the striatum correlates with depressive symptoms and cognitive performance in patients with Parkinson's disease (PD). Twenty patients with PD without major depression and/or dementia (mean age 61.7 Β± 12.7 years) underwent the ^123^IβFPβCIT