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Striatal Dopamine Responses to Intranasal Cocaine Self-Administration in Humans

✍ Scribed by Sylvia M.L. Cox; Chawki Benkelfat; Alain Dagher; J. Scott Delaney; France Durand; Samuel A. McKenzie; Theodore Kolivakis; Kevin F. Casey; Marco Leyton


Book ID
119198164
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
329 KB
Volume
65
Category
Article
ISSN
0006-3223

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Effect of cocaine self-administration on
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An array of evidence indicates that long-term exposure to cocaine alters several components of the brain dopamine system. Because the release of dopamine in the nucleus accumbens (NAc) has been implicated in mediating the reinforcing effects of cocaine, changes in dopamine function can have profound