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Striatal Dopamine D1 receptors in narcolepsy: A PET study with [11C]NNC 756

✍ Scribed by J. O. RINNE; C. HUBLIN; M. PARTINEN; H. RUOTTINEN; K. NÅGREN; P. LEHIKOINEN; U. RUOTSALAINEN; A. LAIHINEN

Book ID
114743923
Publisher
John Wiley and Sons
Year
1996
Tongue
English
Weight
236 KB
Volume
5
Category
Article
ISSN
0962-1105

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NNC 756 ((ϩ)-8-chloro-5-(2,3-dihydrobenzofuran-7-yl)-7-hydroxy-3methyl-2,3,4,5-tetrahydro-1H-3-benzazepine) is a new high affinity dopamine (DA) D 1 receptor antagonist. Labeled with C-11, it has been used as a PET radiotracer to visualize D 1 receptors both in striatal and extrastriatal areas, such