Striatal delivery of CERE-120, an AAV2 v
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Christopher D. Herzog; Biplob Dass; James E. Holden; James Stansell III; Mehdi G
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Article
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2007
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John Wiley and Sons
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English
⚖ 477 KB
## Abstract Neurturin (NTN) is a potent survival factor for midbrain dopaminergic neurons. CERE‐120, an adeno‐associated virus type 2 (AAV2) vector encoding human NTN (AAV2‐NTN), is currently being developed as a potential therapy for Parkinson's disease. This study examined the bioactivity and saf