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Striatal and white matter predictors of estimated diagnosis for Huntington disease

โœ Scribed by Jane S. Paulsen; Peggy C. Nopoulos; Elizabeth Aylward; Christopher A. Ross; Hans Johnson; Vincent A. Magnotta; Andrew Juhl; Ronald K. Pierson; James Mills; Douglas Langbehn; Martha Nance


Book ID
116327083
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
568 KB
Volume
82
Category
Article
ISSN
0361-9230

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## Abstract The relationship between the extent of local gray/white matter atrophy, genetic load, and clinical impairment was studied in Huntington's disease (HD) by means of voxelโ€based morphometry. T1โ€weighted brain images from 33 patients (mean age 49.5, range 25โ€“73 years) with HD duration of 1