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Stress-induced transcription of the endoplasmic reticulum oxidoreductin geneERO1in the yeastSaccharomyces cerevisiae

✍ Scribed by Yukiko Takemori; Ayako Sakaguchi; Sayuri Matsuda; Yu Mizukami; Hiroshi Sakurai

Publisher: Springer
Year: 2005
Tongue: English
Weight: 483 KB
Volume: 275
Category: Article
ISSN: 1617-4615
DOI: 10.1007/s00438-005-0065-9

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## Abstract The endoplasmic reticulum (ER) is important for maintaining the quality of cellular proteins. Various stimuli can disrupt ER homeostasis and cause the accumulation of unfolded or misfolded proteins, i.e., a state of ER stress. Recently, ER stress has been reported to play an important r