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Streptozotocin increased hydroxyl-radicals in pancreatic islets of mice in vitro

✍ Scribed by Patricia Ohly; Lars Gille; Sabine Schulte im Walde; Hans Nohl; Helga Gleichmann

Book ID: 117370077
Publisher: Elsevier Science
Year: 2000
Tongue: English
Weight: 148 KB
Volume: 50
Category: Article
ISSN: 0168-8227
DOI: 10.1016/s0168-8227(00)81981-6

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## Abstract In our previous study, after direct administration of streptozotocin (STZ; 400 μg/g) to fetuses on day 19 of gestation, the B‐cell volume in fetal pancreatic islets showed a marked decrease, but gradually recovered with electron microscopic confirmation of B‐cell regeneration. However,