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Streptomycin biosynthesis in Streptomyces griseus II. Adjacent genomic location of biosynthetic genes and one of two streptomycin resistance genes

✍ Scribed by J. Distler; K. Mansouri; W. Piepersberg


Book ID
109312967
Publisher
John Wiley and Sons
Year
1985
Tongue
English
Weight
384 KB
Volume
30
Category
Article
ISSN
0378-1097

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Gene cluster for streptomycin biosynthes
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A central segment of a cluster of biosynthetic genes for the antibiotic streptomycin cloned from Streptomyces griseus was analysed for open reading frames, as well as for transcriptional and translational activity. The nucleotide sequence revealed two significant open reading frames, ORF1 and APH(6)