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Streamlined Process for the Conversion of Artemisinin to Artemether

✍ Scribed by Stringham, Rodger W.; Teager, David S.

Book ID
120572102
Publisher
American Chemical Society
Year
2012
Tongue
English
Weight
254 KB
Volume
16
Category
Article
ISSN
1083-6160

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✍ Charles W. Jefford; Maria G. H. Vicente; Yvan Jacquier; France Favarger; Jiri Ma 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 German ⚖ 854 KB

## Abstract The treatment of artemisinin (1) and β‐artemether (6) with Zn dissolving in AcOH for a few hours results in mono‐deoxygenation giving deoxyartemisinin (5) and deoxy‐β‐artemether (7), respectively, as the sole product. In contrast, submission of 1 to FeCl~2~ · 4 H~2~O in MeCN at room tem