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Streamlined process development using the Micro24 Bioreactor system

✍ Scribed by Warr, Steve RC; Betts, John PJ; Ahmad, Shahina; Newell, Katy V; Finka, Gary B


Book ID
121591491
Publisher
BioMed Central
Year
2013
Tongue
English
Weight
385 KB
Volume
7
Category
Article
ISSN
1753-6561

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An agitated 12-well microtiter plate system with a working volume of 2ml was investigated for cell culture process development. Agitation assures homogeneity in wells and enhances mass transfer between the gas and the liquid phase, thus improving maximum cell density and pH stability. The pH of the