Optimization of release kinetics from su
β
Cristina Maderuelo; ArΓ‘nzazu Zarzuelo; JosΓ© M. Lanao
π
Article
π
2011
π
John Wiley and Sons
π
English
β 425 KB
In the present work, a single model-independent approach was developed to optimize the release kinetics of drugs from sustained-release formulations, using stavudine (d4T) as a model drug. This approach is based on the pharmacokinetic simulation of drug plasma levels through a semiparametric approac