✦ LIBER ✦

Strategy for sequencing oligopeptides using positive and negative ion laser desorption fourier transform mass spectrometry

✍ Scribed by Liub-Chii Yang; Charles L. Wilkins

Book ID: 102964737
Publisher: John Wiley and Sons
Year: 1989
Tongue: English
Weight: 508 KB
Volume: 24
Category: Article
ISSN: 1076-5174
DOI: 10.1002/oms.1210240609

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✦ Synopsis

A laser desorption Fourier transform mass spectrometric (LD/FTMS) method that uses both positive and negative ion LD/FT mass spectra obtained with collision-activated dissociation has been developed for analysis of oligopep tides. The technique is demonstrated using the model compound gramicidin D, for which the correct sequence is derived using only LD/ITMS information. Different relatiomhips between positive and negative ion spectra are found for linear and cyclic oligopeptides.

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