Lamivudine treatment in patients with chronic hepatitis B virus (HBV) infection may improve clinical state and suppress viral replication before liver transplantation. Emergence of lamivudine-resistant YMDD mutant is common. We report the results of liver transplantation in 16 patients with pretrans
Strategy for lamivudine-resistant YMDD mutant-associated chronic hepatitis B
β Scribed by Kendo Kiyosawa; Eiji Tanaka
- Book ID
- 106182426
- Publisher
- Springer Japan
- Year
- 2001
- Tongue
- English
- Weight
- 53 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0944-1174
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract Hepatitis B virus (HBV) mutants with mutations in the YMDD motif of viral DNA polymerase/reverse transcriptase are described in patients infected with HBV who have not received lamivudine therapy, but their pathogenetic potential is not clear. These mutants were detected by the polymera
## Abstract Although the rate at which mutations in the tyrosineβmethionineβaspartateβaspartate (YMDD) motif of hepatitis B virus polymerase form is high during prolonged lamivudine (LAM) therapy, these mutations sometimes occur naturally in treatmentβnaΓ―ve patients with chronic hepatitis B. The pr