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Strategies of protection from nitric oxide toxicity in islet inflammation

✍ Scribed by H. Rothe; H. Kolb


Book ID
105797470
Publisher
Springer
Year
1999
Tongue
English
Weight
90 KB
Volume
77
Category
Article
ISSN
0946-2716

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Nitric oxide (NO) has cytotoxic effects but NO producing neurons are resistant to NO toxicity. These results suggest the presence of self-protecting factors for NO toxicity. Recently, 6R-tetrahydrobiopterin (6R-BH 4 ), a cofactor for NO synthase (NOS), has been reported to degrade NO raising the pos