Analysis of integrated hepatitis B virus
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Hisashi Matsumoto; Tetsuo Yoneyama; Keiji Mitamura; Toshiaki Osuga; Hiroto Shimo
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Article
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1988
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John Wiley and Sons
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French
โ 631 KB
By digestion with Hindlll restriction enzyme, a human hepatocellular carcinoma was shown to contain only 2 hepatitis B virus (HBV) DNA inserts. Both Hindlll fragments (8 and 16 kb) were molecularly cloned and the structures of HBV DNA and adjacent host sequences were analyzed. One clone (AYH 8) cont