In this work, an integrated PAT approach was developed for monitoring a pharmaceutical (naproxen) and a polymer (eudragit) coprecipitation process: real-time in-line near-infrared (NIR) absorbance monitoring, real-time on-line turbidity monitoring, and in situ crystal size monitoring. The data and i
✦ LIBER ✦
Strategic funding priorities in the pharmaceutical sciences allied to Quality by Design (QbD) and Process Analytical Technology (PAT)
✍ Scribed by Buket Aksu; Thomas De Beer; Staffan Folestad; Jarkko Ketolainen; Hans Lindén; Joao Almeida Lopes; Marcel de Matas; Wim Oostra; Jukka Rantanen; Marco Weimer
- Book ID
- 116438683
- Publisher
- Elsevier Science
- Year
- 2012
- Tongue
- English
- Weight
- 152 KB
- Volume
- 47
- Category
- Article
- ISSN
- 0928-0987
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
Quality-by-Design (QbD): An integrated p
✍
Huiquan Wu; Mansoor A. Khan
📂
Article
📅
2010
🏛
John Wiley and Sons
🌐
English
⚖ 359 KB
👁 1 views
Quality-by-design: An integrated process
✍
Huiquan Wu; Mansoor A. Khan
📂
Article
📅
2011
🏛
John Wiley and Sons
🌐
English
⚖ 595 KB
The objective of this study was to demonstrate the feasibility of using an integrated process analytical technology (PAT) approach to determine nucleation and growth mechanisms of a dynamic naproxen (drug)-Eudragit L100 (polymer) coprecipitation process. The influence of several thermodynamically im
Quality assurance in design: Quality Ass