Strand scission in DNA by Gossypol and C
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Zaidi, Rana ;Hadi, S. M.
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Article
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1992
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John Wiley and Sons
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English
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Gossypol, a polyphenolic binaphthyl dialdehyde found in cotton seeds, is a dietary mutagen and a potential male contraceptive. In the presence of CdII), gossypol caused breakage of supercoiled plasmid pBR322 DNA. The products were relaxed circles or a mixture of these and linear molecules. Other met