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Strain difference in regulatory mechanism of P2X7 receptor expressed by cultured mouse astrocytes

✍ Scribed by Yuka Kido; Chiyo Kawahara; Yasuko Terai; Manami Fukagawa; Jyunki Kato; Yukari Dohi; Hiroto Okuda; Nishida Kentaro; Kazuki Nagasawa

Book ID
116777563
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
78 KB
Volume
68
Category
Article
ISSN
0168-0102

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## Abstract Nucleotides and nucleosides play important roles by maintaining brain homeostasis, and their extracellular concentrations are mainly regulated by ectonucleotidases and nucleoside transporters expressed by astrocytes. Extracellularly applied NAD^+^ prevents astrocyte death caused by exce