Sex and strain differences in the hepato
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Boyer, C. Scott ;Ross, David ;Petersen, Dennis R.
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Article
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1988
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John Wiley and Sons
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English
⚖ 660 KB
Cocaine-induced hepatotoxicity was examined in vivo in a dose-responsive manner in C57BL/6Ibg, DBA/2Ibg, C3H/2Ibg, and Balb/cJ mice. Serum glutamic-pyruvic transaminase (SGPT) activities were determined 24 hours after intraperitoneal (IP) administration of cocaine (20 to 100 mg/kg). Significant elev