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Store-operated Ca2+ release in skeletal muscle: tailored for a specialized system

✍ Scribed by G. D. Lamb


Book ID
110115768
Publisher
Cambridge University Press
Year
2007
Tongue
English
Weight
166 KB
Volume
583
Category
Article
ISSN
0022-3751

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## Abstract Overexpression of IGF‐1 in C2C12 myoblasts causes hypertrophy when myoblasts fuse to form myotubes, a response that requires elevated intracellular calcium. We show that myoblasts contain a store‐operated Ca^2+^ channel (SOCC) whose activity is enhanced with IGF‐1 overexpression. A memb