Storage and Release of Tissue Plasminogen Activator by Sympathetic Axons in Resistance Vessel Walls
β Scribed by Xi Jiang; Yafei Wang; Arthur R. Hand; Concettina Gillies; Robert E. Cone; Jayson Kirk; James O'Rourke
- Book ID
- 115641314
- Publisher
- Elsevier Science
- Year
- 2002
- Tongue
- English
- Weight
- 279 KB
- Volume
- 64
- Category
- Article
- ISSN
- 0026-2862
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Tissue plasminogen activator (t-PA) is expressed by hypothalamic and peripheral sympathetic neurons. The sympathetic axons that permeate artery walls have not been investigated as possible sources of intramural t-PA. The plasmin produced by such a system would locally activate both fibrinolysis and