✦ LIBER ✦
Stoffwechselprodukte von Mikroorganismen 198. Mitteilung Die Eurekansäure, ein Abbauprodukt von Flambamycin und Avilamycin: Konfigurationsbestimmung durch Röntgenstrukturanalyse und Abbau
✍ Scribed by Ernst Kupfer; Katarina Neupert-Laves; Max Dobler; Walter Keller-Schierlein
- Publisher
- John Wiley and Sons
- Year
- 1980
- Tongue
- German
- Weight
- 460 KB
- Volume
- 63
- Category
- Article
- ISSN
- 0018-019X
No coin nor oath required. For personal study only.
✦ Synopsis
Eurekanic Acid, a Degradation Product of Flambamycin and Avilamycin: Determination of the Configuration by X‐Ray Structural Analysis and Degradation
The relative configuration of methyl O‐acetyleurekanate (6), obtained by mild methanolysis of avilamycin A (2) and subsequent acetylation, was determined by an X‐ray structural investigation. Methyl dihydroeurekanate (7), similarly obtained from avilamycin C (3) and from reduced avilamycin A methyl ether, was degraded to L‐threonolactone (14) which allowed to determine the chirality of eurekanic acid (4).