Stochastic theory of two-site adsorption chromatography by the characteristic function method

✍ Scribed by Alberto Cavazzini; Maurizio Remelli; Francesco Dondi

• Publisher: John Wiley and Sons
• Year: 1997
• Tongue: English
• Weight: 110 KB
• Volume: 9
• Category: Article
• ISSN: 1040-7685
• DOI: 10.1002/(sici)1520-667x(1997)9:4<295::aid-mcs7>3.0.co;2-x

✦ Synopsis

The problem of two-site adsorption chromatography under linear conditions is considered by using the molecular dynamic theory of chromatography originally developed by Giddings and Eyring. The probabilistic description is made by using the characteristic function method, and the solution is obtained under the most general conditions of both stationary phase entry process and site desorption process. Relevant chromatographic attributes such as the C term of van Deemter equation and the peak skewness and excess are investigated with reference to column heterogeneity.