Stochastic mixture of absolute and relative priorities in GI|HM2|1 queue

Long-distance control in stereoselective

Long-distance control in stereoselective reduction of 3-[3-(4′-bromo[1,1′-biphenyl]-4-yl)-3-keto-1-phenylpropyl]-4-hydroxy-2H-1-benzopyran-2-one: Relative configuration of prevailing diastereomer and absolute configuration of its enantiomers

✍ Amir Avdagić; Livius Cotarca; Zdenko Hameršak; Miklos Hollòsi; Zsuzsa Majer; Edi 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 254 KB 👁 1 views

Depending on the reducing agent and reaction conditions, diastereoselective reduction of 3-[3-(4Ј-bromo[1,1Ј-biphenyl]-4-yl)-3-keto-1-phenylpropyl]-4hydroxy-2H-1-benzopyran-2-one (2) proceeds with different stereoselectivity; a surprisingly high, approximately 90% d.e. of 4A is achieved with NaBH 4