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Stimulus-transcription coupling and immediate-early genes: Correlations and molecular mechanisms

✍ Scribed by Michael J. Iadarola


Book ID
119587764
Publisher
Elsevier Science
Year
1994
Weight
362 KB
Volume
3
Category
Article
ISSN
1058-9139

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Long-term changes in gene expression appear to be critical to the formation of memory, but little is known about its stimulus-transcription coupling. Numerous studies in the last decade, by focusing on unraveling this signal transduction pathway, have investigated the potential role of the immediate

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## Abstract The immediate‐early gene __Zif268__ is a member of the Egr family of inducible transcription factors. Data from gene expression studies have suggested that this gene may play a critical role in initial triggering of the genetic machinery that has long been considered a necessary mechani