Stimulative effect of serum on the growth of HeLa cells suppressed in a K+-deficient chemically defined medium
β Scribed by Tetsuhiro Sakai; Toshitaka Ikehara; Hiroshi Miyamoto; Kenichi Kaniike
- Book ID
- 118940513
- Publisher
- Elsevier Science
- Year
- 1981
- Tongue
- English
- Weight
- 439 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0024-3205
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## Abstract Hydrocortisone modulates the binding capacity of HeLa cells for ^125^Iβlabeled epidermal growth factor (EGF). A twofold increase in ^125^Iβlabeled EGF binding is observed within 24 hours after the addition of pharmacological concentration of hydrocortisone (5 Γ 10^β8^β1 Γ 10^β6^ M). Thi
The influence of the intracellular K+ concentration on the effects of growth factors (insulin, EGF, hydrocortisone, and transferrin) and LDL on growth of HeLa cells was investigated. Upon replacement of K t in a chemically defined medium (K+-CDM) by Rb+ (Rb+-CDM), about 80% of the intracellular K t