Stimulation of uterine nonhistone protein phosphorylation and nuclear protein kinase activity by estradiol-17β
✍ Scribed by Michael E. Cohen; Lewis J. Kleinsmith
- Book ID
- 115746381
- Publisher
- Elsevier Science
- Year
- 1976
- Weight
- 460 KB
- Volume
- 435
- Category
- Article
- ISSN
- 0005-2787
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract Early growth response‐1 (__Egr‐1__) is an immediate‐early gene induced by E2 in the rodent uterus and breast cancer cells. E2 induces Egr‐1 mRNA and protein levels in MCF‐7 human breast cancer cells and reporter gene activity in cells transfected with pEgr‐1A, a construct containing the
## Abstract Estrogenic compounds can activate protein kinase C (PKC), which is a calcium and phospholipid‐dependent serine/threonine kinase. In the present study, we investigated the role of 17β‐estradiol (E2), diethylstibestrol (DES), and bisphenol A (BPA) in the phosphorylation of substrate by PK
Nuclear matrix (NM), a proteinaceous network of filaments, dictates nuclear morphology and the structure/function of DNA. Phosphorylation of NM proteins is a potential signal for regulating matrix functions. Histones also are intimately involved in DNA structure and transcription. Here, we report th