Stimulation of tumor cell growth by vasoactive intestinal peptide
β Scribed by Eric M. Scholar; Sudhir Paul
- Publisher
- John Wiley and Sons
- Year
- 1991
- Tongue
- English
- Weight
- 347 KB
- Volume
- 67
- Category
- Article
- ISSN
- 0008-543X
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The structure of the vasoactive intestinal peptide 1-28 in 40% 2,2,2-trifluoroethanol was investigated by two-dimensional 'H-nmr spectroscopy. All 'H resonances, except the y, 6, and c protons of the lysine residues, could be sequentially assigned. Numerous intraresidual as well as short-range inter
Vasoactive intestinal peptide (VIP) is a neuromodulator and growth regulator in the developing nervous system. We analyzed 10 primitive neuroectodermal tumor (PNET) cell lines, 29 central PNET (cPNET) and 17 tumors of the Ewing's sarcoma/peripheral PNET family (ESFT) using reverse transcriptase-poly
## Abstract The structural features of vasoactive intestinal peptide (VIP) and of its Gln^16^βdiaminopropane derivative (VIPβDAP) in solution were investigated by limited proteolysis experiments with trypsin and thermolysin. The proteolysis of the native peptide by both proteinases takes place near
## BACKGROUND. Vasoactive intestinal peptide (VIP) is one of several small neuropeptides that affect cancer growth. A lipophilic VIP analog, stearyl-Nle 17 -neurotensin 6-11 VIP 7-28 (SNH) that inhibited lung carcinoma growth has been described previously. The experiments performed were clonogenic