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STIMULATION OF THE MURINE IMMUNE SYSTEM BY ANTI-IgD ANTIBODIES: A POLYCLONAL MODEL OF B-LYMPHOCYTE ACTIVATION BY A THYMUS DEPENDENT ANTIGEN

โœ Scribed by Fred D. Finkelman; Linda M. Muul; Lyn Yaffe; Irwin Scher; James J. Mond; Steven W. Kessler; John Ryan; John T. Kung; and Eleanor S. Metcalf

Book ID
118719742
Publisher
John Wiley and Sons
Year
1982
Tongue
English
Weight
768 KB
Volume
399
Category
Article
ISSN
0890-6564

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The injection of mice with 800 micrograms of an affinity-purified goat antibody to mouse IgD (GaM delta) induces early, T-independent polyclonal increases in the expression of B cell surface Ia, and B cell size and DNA synthesis, as well as later, T-dependent polyclonal increases in spleen cell numb