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Stimulation of receptor-dependent and receptor-independent pathways of low-density lipoprotein degradation in arterial smooth muscle cells by platelet-derived growth factor

✍ Scribed by Alan Chait; Russell Ross; Edwin L. Bierman


Book ID
115739927
Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
618 KB
Volume
960
Category
Article
ISSN
0005-2760

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## Abstract The low density lipoprotein receptor related protein‐1 (LRP‐1) is a cargo transport receptor that undergoes constitutive endocytosis and recycling. Platelet‐derived growth factor‐BB (PDGF‐BB) binds to LRP‐1 and may bridge LRP‐1 to PDGF receptors. Bridging of LRP‐1 to other receptors by